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Featured Updates
June 30, 2025
In support of recent security directives, NIH is implementing a technical update to enhance security measures focused on protecting data provided by NIH Controlled-Access Data Repositories. Specifically, as of May 5, 2025, NIH requires that distribution agreements be valid for a period no longer than one year. If you have active requests for newer versions of these distributions or to other distributions, your access to those versions/distributions will be unaffected by this change. You may refer to your user dashboard for your currently active requests: https://www.nimhgenetics.org/approval/user/ (login required). Please be advised the distribution agreement now only grants access for a maximum of one year.
Per the terms of the distribution agreement, you may not keep any raw data files or biospecimens without active access to a version of the source distribution. To maintain access to these distributions and/or request new distribution you will need to complete a new access request: https://www.nimhgenetics.org/request-access/how-to-request-access. If you are requesting access with substantially the same study description as in your prior request, your cover letter should include a progress report on what was accomplished for your last request (publications, locations of secondary analyses uploads, etc.)
Additionally, if you are looking for access to the CommonMind and/or the PsychENCODE Consortium Distribution(s) formerly accessible through Synapse/NRGR, these data are now only available through the NIMH Data Archive (NDA). More information about how to request access through NDA is available on the Getting Access to Shared Data page on the NDA website.
Please contact the NIMH Genomics Resources Program Office for any questions or concerns: NIMH.genomics.resources@mail.nih.gov.
February 12, 2025
The Induced Pluripotent Stem Cell (IPSC) Distribution v11.6 was published on 2025-02-12. IPSC distribution v11.6 includes 1546 subjects, 1512 of whom have at least one biosample on record at the repository. There are 830 IPSCs, 627 FCLs, and 8 OEs as of the release. In addition to case/control studies, the IPSC collection includes 11 family studies. The most recent update adds the following studies: Study 136 (Hallmayer) includes 66 individuals, 66 of whom have at least one biosample on record at the repository. There are 58 FCLs and 36 IPSCs. Study 161 (Chung) includes 12 individuals, 12 of who have at least one biosample on record at the repository. There are 18 IPSCs. Study 182 (Duan) includes 60 individuals, 60 of whom have at least one biosample on record at the repository. There are 90 IPSCs. Study 192 (Mulle) includes 96 individuals, 96 of whom have at least one biosample on record at the biorepository. There are 11 IPSCs. Study 195 (Buxbaum; Brennand) includes 92 individuals, 92 of whom have at least one biosample on record at the biorepository. There are 179 IPSCs.
February 12, 2025
The Schizophrenia (SZ) Distribution v20.7 was published on 2025-02-12. SZ Distribution v20.7 includes 64408 individuals, 47472 of whom have at least one biosample on record at the repository. In addition to case/control studies, the Schizophrenia collection includes 18 family studies, one or more of which are large/multigenerational. The following studies have been added to the collection: Study 136 (Hallmayer) includes 66 individuals, 66 of whom have at least one biosample on record at the repository. Study 148 (Goldstein; Pulver) includes 235 individuals, 235 of whom have at least one biosample on record at the repository. Study 161 (Chung) includes 12 individuals, 12 of who have at least one biosample on record at the repository. Study 189 (Freimer) includes 9204 individuals, 9204 of whom have at least one biosample on record at the repository. Study 192 (Mulle) includes 96 individuals, 96 of whom have at least one biosample on record at the biorepository. Study 195 (Buxbaum; Brennand) includes 92 individuals, 92 of whom have at least one biosample on record at the biorepository.
February 12, 2025
The 22q11.2 Deletion Syndrome (22Q) Collection v1.6 was published on 2025-02-12. 22Q Distribution v1.6 includes 501 subjects, 488 of whom have at least one biosample on record at the biorespository. The most recent update adds the following study: Study 136 (PI: Hallmayer) includes 66 individuals, 66 of whom have at least one biosample on record at the biorepository.
December 13, 2024
The Bipolar Disorder (BP) Distribution v12.5 was published on 2024-12-09. BP Distribution v12.5 includes 26781 subjects, 20079 of whom have at least one biosample on record at the repository. In addition to case control studies, the BP collection includes 10 family studies, one or more of which include families that are large and/or multigenerational. The most recent updates adds the following studies: Study 101 (PIs: Nurnberger, Kelsoe, Coryell, Lohoff, Berrettini, Odegaard, McInnis, Nievergelt) includes 381 individuals, 381 of whom have at least one biosample on record at the repository. Study 179 (PI: Blumberg) includes 16 individuals, 16 of whom have at least one biosample on record at the repository. Study 184 (PIs: Gage, Song) includes 17 individuals, 17 of whom have at least one biosample on record at the repository. Study 188 (PI: Blumberg) includes 81 individuals, 79 of whom have at least one biosample on record at the repository.
December 13, 2024
The Induced Pluripotent Stem Cell (IPSC) Distribution v11.5 was published on 2024-12-09. IPSC Distribution v11.5 includes 1306 subjects, 1272 of whom have at least one biosample on record at the repository. There are 565 IPSCs, 626 FCLs, and 8 OEs as of the release. In addition to case/control studies, the IPSC collection includes 10 family studies. The most recent update adds the following studies: Study 101 (PIs: Nurnberger, Kelsoe, Coryell, Lohoff, Berrettini, Odegaard, McInnis, Nievergelt) includes 381 individuals, 381 of whom have at least one biosample on record at the repository. There are 10 IPSCs. Study 184 (PIs: Gage, Song) includes 17 individuals, 17 of whom have at least one biosample on record at the repository. There are 7 FCls and 24 IPSCs.
October 02, 2024
The Research Domain Criteria (RDOC) Distribution v2.2 was published on 2024-10-02. RDOC Distribution v2.2 includes 6797 subjects, 4519 of whom have at least one biosample on record at the repository. In addition to case/control studies, the RDOC Collection includes 4 family studies, 1 of which includes families that are large and/or multigenerational. The most recent update add or updates the following studies: Study 147 (PIs: Faraone, Glatt) includes 3451 individuals, 2448 of whom have at least one biosample on record at the repository. Study 171 (PI: Roberson-Nay) includes 645 individuals, 307 of whom have at least one biosample on record at the repository.
October 02, 2024
The Eating Disorders (ED) Distribution v3.2 was published on 2024-10-02. ED Distribution v3.2 includes 8793 subjects, 7469 of whom have at least one biosample on record at the repository. In addition to case/control studies, the ED Collection includes 1 family study, which includes families that are large and/or multigenerational. The most recent update adds or updates the following studies: Study 133 (PIs: Bardone-Cone, Bulik) includes 169 individuals, 169 of whom have at least one biosample on record at the repository.